Conventional silica based HPLC stationary phases are usually bonded with mono-type alkyl chain molecules, e.g., C18,C8, etc. Recent studies have revealed that synergistic effects can be obtained when the bonded surface consists of C18 mixed with a shorter chain such as C8, amide or nitro-phenyl, etc. These new products offer different selectivity,coordinating multi-functionality, as well as a spacer effect (C18/C8).
Improved performance from a mixed-phase C18/C8 (1:1) column compared to mono-chain C18 or C8 columns
A mixed-phase of C18 and propionic amide provides unique selectivity which allows extremely polar and non-polar compounds to be analyzed in a single run under isocratic conditions.
Mix-phase of SCX and C18，balanced retention for polar (basic) and non-polar; very useful for analysis of multi-components, unique selectivity, LC-MS compatible.